Arsenic and Old Lace is a 1944 film directed by Frank Capra based on Joseph Kesselring's play of the same name. The script adaptation was by twins Julius J. Epstein and Philip G. Epstein. Capra actually filmed the movie in 1941, but it was not released until 1944, after the original stage version had finished its run on Broadway. The lead role of Mortimer Brewster was originally intended for Bob Hope, but he couldn't be released from his contract with Paramount. Capra had also approached Jack Benny and Ronald Reagan before going with Cary Grant. Boris Karloff played Jonathan Brewster, who "looks like Karloff", on the Broadway stage, but he was unable to do the movie as well because he was still appearing in the play during filming, and Raymond Massey took his place.
In addition to Grant as Mortimer Brewster, the film also starred Josephine Hull and Jean Adair as the Brewster sisters, Abby and Martha, respectively. Hull and Adair as well as John Alexander (who played Teddy Roosevelt) were reprising their roles from the 1941 stage production. Hull and Adair both received an eight-week leave of absence from the stage production that was still running, but Karloff did not as he was an