Top List Curated by Listnerd
  • Public list
  • Nov 27th 2012
  • 461 views
  • 618 votes
  • 618 voters
  • 27%
Best Gene Group Membership Evidence of All Time

More about Best Gene Group Membership Evidence of All Time:

Best Gene Group Membership Evidence of All Time is a public top list created by Listnerd on rankly.com on November 27th 2012. Items on the Best Gene Group Membership Evidence of All Time top list are added by the rankly.com community and ranked using our secret ranking sauce. Best Gene Group Membership Evidence of All Time has gotten 461 views and has gathered 618 votes from 618 voters. O O

Best Gene Group Membership Evidence of All Time is a top list in the Science category on rankly.com. Are you a fan of Science or Best Gene Group Membership Evidence of All Time? Explore more top 100 lists about Science on rankly.com or participate in ranking the stuff already on the all time Best Gene Group Membership Evidence of All Time top list below.

If you're not a member of rankly.com, you should consider becoming one. Registration is fast, free and easy. At rankly.com, we aim to give you the best of everything - including stuff like the Best Gene Group Membership Evidence of All Time list.

Get your friends to vote! Spread this URL or share:

Items just added

    16
    7.60
    5 votes
    23
    7.00
    5 votes
    33
    DNA repair

    DNA repair

    DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages. The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA,
    7.75
    4 votes
    105

    SOS response

    The SOS response is a global response to DNA damage in which the cell cycle is arrested and DNA repair and mutagenesis are induced. The system involves the RecA protein (Rad51 in eukaryotes). The RecA protein, stimulated by single-stranded DNA, is involved in the inactivation of the LexA repressor thereby inducing the response. It is an error-prone repair system. The SOS response was discovered and named by Miroslav Radman in 1975. During normal growth, the SOS genes are negatively regulated by LexA repressor protein dimers. Under normal conditions, LexA binds to a 20-bp consensus sequence (the SOS box) in the operator region for those genes. Some of these SOS genes are expressed at certain levels even in the repressed state, according to the affinity of LexA for their SOS box. Activation of the SOS genes occurs after DNA damage by the accumulation of single stranded (ssDNA) regions generated at replication forks, where DNA polymerase is blocked. RecA forms a filament around these ssDNA regions in an ATP-dependent fashion, and becomes activated. The activated form of RecA interacts with the LexA repressor to facilitate the LexA repressor's self-cleavage from the operator. Once the
    8.00
    2 votes
    139
    8.00
    1 votes
    165
    6.50
    2 votes
    177
    7.00
    1 votes
    210
    5.00
    1 votes
    Get your friends to vote! Spread this URL or share:

    Discuss Best Gene Group Membership Evidence of All Time

    Top List Voters